Martinsburg is on I-81 between Hagerstown, Maryland to the north and Winchester, Virginia to the south.
Amtrak
229 E Martin Street, (http://www.amtrak.com/ser...). Open 5AM to 9PM Monday through Friday; closed Saturday and Sunday. Martinsburg is on the Capitol Limited line, which runs daily between Washington, D.C. and Chicago.Maryland Rail Commuter
226 E Martin Street, 304-263-3376, (http://www.commuterpage.c...). Open 5AM to 9AM and 6PM to 8:30PM Monday through Friday. Martinsburg is on the Brunswick line, which ferries passengers to Washington, D.C..